????б??????????????????????????????????????????????????????????????IPD??

?????????????????????????????????Monod Bio???600???????????ù????????????University of Washington????????????о?????Institute for Protein Design?????“IPD”????????????????????????IPD???????????Neoleukin Therapeutics??

Monod Bio????????????????????????????????????????????????????????????????IPD?????????????????????????????????б????????????

??????????????????IPD??Rosetta?????????????????????μ??????????????????????????????????????????

Monod Bio????????CSO??Alfredo Quijano Rubio?????GeekWirey??????????“???????????Monod Bio???????????????????????????????????????????”?????????????????????1?????Monod Bio??????????????????????????????????????

Alfredo Quijano Rubio?????о??????????IPD??David Baker???????????????????????????????????б????????????

??2021??1?·?????Nature????????о?????У?Alfredo Quijano Rubio??David Baker??????????????????????COVID-19????“???”????????????????????????????????????????????????????????????????HER2????????????????????????????????????????????

Monod Bio?????й??CEO??Daniel-Adriano Silva???“??????????????????????????????????????????Щ?????ε??????????????豸??????????”

???磬?????????????????????????????????????????????????Daniel-Adriano Silva?????????????·???????????????????????????????????м??

????Monod Bio?????й?Daniel-Adriano Silva?????????Alfredo Quijano Rubio??????????David Shoultz

2021????Daniel-Adriano Silva??Neoleukin Therapeutics??????о??????????????????????1?????????Neoleukin Therapeutics????????????COVID-19?????????David Shoultz??ù??COVID-19??????????“????????????????David Shoultz???н?????????μ??????????????”Daniel-Adriano Silva?????

?1??????????齨????????????????Neoleukin Therapeutics?????????Alfredo Quijano Rubio?????David Shoultz??David Shoultz????????1??????????????????????

Monod Bio?????????????????IPD????David Baker??IPD?????Andy??Hsien Wei??Yeh?? VelosBio??????й?Dave Johnson??VelosBio???Merck??27.5??????????

Monod Bio?????2021??11????????????????У???CoMotion??????????2021??12?￡?????????????????????????????600??????????????????

??????к??IPD?????????????????磬Cyrus Biotechnology????Ｏ??1800???????????90???????????????????????A-Alpha Bio?Ｏ??2000???????Icosavax??????????У????Ｏ??1.8???????????????COVID-19?????????????????з???????

2021??12?￡?IPD?о??????????????????????????????????????Science???“??????”????Monod Bio??????????????IPD????????????????????Rosetta?????

Monod Bio???????????????????????????????????????????????＼?????????????????б?????μ????????????????????????????е?б???м??

IPD?о?????????????????COVID-19???????е????????????????????????????????????????????BioRxiv?????ж??????????????????????

????????https://www.biorxiv.org/content/10.1101/2021.06.22.449355v1

Monod Bio???????????????????????????????ɡ?????????????б?????????????б???????????????????????????????????￡?????????????????????????????????????????????????????????????????????????????????????????

???б?????????????????????????????“Alfredo Quijano Rubio??????????黯??????????”Daniel-Adriano Silva?????

????б??????????????????????????????????????????????????????????????????????乹??Allostery????????Ч??????????????????????????????乹Ч????????????????????????Jacques Monod?????????20????60?????????

????Monod Bio????????????????????????????ù?????????????????????г????????????????????????2022????????????????15??20???????

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